Administrative Supplements to Add Research on Alzheimer’s Disease and Alzheimer’s Disease-Related Dementias


NIGMS, along with other NIH Institutes and Centers, has partnered with the National Institute on Aging to grow the community of scientists actively engaged in research focused on Alzheimer’s Disease and Alzheimer’s Disease-Related Dementias (AD/ADRD). Details of this year’s AD/ADRD supplement program are provided in NIA’s Notice NOT-AG-18-008. If your research, research training, or research capacity-building grant is not currently focused on AD/ADRD and you have an inspiring new idea of potential value to the field that is within the scope of the funded Specific Aims of your current award, please consider this opportunity.

Research related to AD/ADRD might fall within the scope of an already-funded NIGMS award originally focused on, for example, an enzyme, transporter, or metabolic pathway being studied for its basic biological or physiological role (or a non-AD/ADRD-related medical condition) if you have recognized an exciting new implication for AD-type pathologies or their treatment. Funded projects developing analytical methods, tools or technologies, drug molecules, or drug delivery systems not previously intended for application to AD/ADRD might now appear to have potential in this area. Potential applicants are strongly encouraged to contact their program director to discuss their ideas for AD/ADRD research and how those relate to the Specific Aims currently funded. Decisions about scope are strictly the purview of NIH. Center and Resource grants that allow non-specified pilot projects should consider adding AD/ADRD projects if interest and expertise exist.

NIA provides an Alzheimer’s Disease Administrative Supplements webpage that includes NIH’s coding definitions of Alzheimer’s disease and its related dementias, as well as titles and abstracts for several funded projects that meet the definition of AD/ADRD research. These sources can help you determine if your grant is already considered AD/ADRD research and, therefore ineligible for this supplement. If the Specific Aims of your grant are not already AD/ADRD-related and you’d like to apply for this supplement, you are strongly encouraged to use the information on NIA’s supplement webpage as well as the Query and Matchmaker tools in NIH RePORTER to help assure that the research in your supplement request is considered AD/ADRD-appropriate.

Applications must be received at NIGMS by June 8 for funding in FY 2018. Applicants must use NIH’s general Administrative Supplement Funding Opportunity Announcement, PA-18-591. To ensure that NIGMS can quickly identify applications for AD/ADRD supplements, be sure to include the NIA Notice number (NOT-AG-18-008) in the abstract and notify the Program Official of the parent award that a supplement request has been submitted. Applications will be ranked by NIGMS and the most compelling will be submitted to NIA for final consideration.

Additional requirements: Eligible NIGMS grants must:

  • Have a project end date in FY 2019 or later (on or after October 1, 2018).
  • Not be in a no-cost extension or entering a no-cost extension in FY 2018 (on or before September 30, 2018).
  • Be eligible for a supplement. R35 MIRA grants are not eligible for this supplement program, per NOT-AG-18-008. R15 AREA grant PIs should check with their Program Official or Grant Specialist about the possibility of supplement awards.

Please contact me if you have questions regarding the details of this administrative supplement program, and include NOT-AG-18-008 in the subject line of all related email communication.

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