Although NIGMS is not the only source of federal funding for sepsis research, the Institute supports a substantial portfolio of research that includes both fundamental and clinical studies, from the molecular to the organismal, that emphasizes the host’s response rather than causative factors such as infection or injury. In an effort to more rapidly move NIGMS’ sepsis research program and its translation forward, we’ve issued a Request for Information (RFI) to obtain feedback, comments, novel ideas, and strategies that address the challenges and opportunities in sepsis research to accelerate advances in detection of and treatment for this condition.
A recent analysis by NIGMS staff has uncovered some promising results for women entering academic positions in the biomedical sciences. The study, which published today in the Proceedings of the National Academy of Sciences (PNAS), found that once men and women receive their first major NIH grant, their funding longevity is similar. The data contradict the common assumption that, across all career stages, women are at a large disadvantage compared to men.
The results of the analysis should be encouraging for women interested in becoming independent investigators, since the likelihood of sustaining NIH grant support may be better than commonly perceived. You can read the full study, “NIH Funding Longevity by Gender,” in the current edition of PNAS.
NIGMS is committed to supporting a wide-ranging portfolio of biomedically relevant fundamental research. As we discussed in a previous Feedback Loop post, we see this approach as the best way to increase our understanding of life. For many years, one important dimension of diversity in our scientific portfolio—the organisms scientists use to conduct their research—was limited by technical considerations. However, recent advances such as the decreasing cost of genome sequencing and the development of the CRISPR system for genetic modification now make it possible to use an expanded range of research organisms.
We’re recruiting for a program director (also known as a health scientist administrator or program officer) to manage research grant, fellowship, training, and other types of awards focused on the structure and function of cells and cellular components, and the cellular and molecular mechanisms that underlie inheritance, gene expression, and development. The position is in our Division of Genetics and Molecular, Cellular, and Developmental Biology, and it involves working collaboratively with other program directors in the division to support outstanding science in these fields. Candidates should have expertise in state-of-the-art molecular genetics, cell biology, and/or developmental biology. Familiarity with NIH extramural funding as an applicant, reviewer, or NIH scientific administrator is a plus, and outstanding written and oral communication skills are essential. Continue reading
UPDATE: The Initiative for Maximizing Student Development (IMSD) funding opportunity announcement is now available.
NIGMS has a longstanding commitment to developing a diverse pool of biomedical scientists through a variety of institutional training and student development programs. Based on stakeholders’ feedback through Requests for Information (NOT-GM-15-108; NOT-GM-17-017), as well as extensive analyses and discussions with NIH staff and the community, we intend to make adjustments to our programs designed to enhance the diversity in the biomedical research workforce. The modifications, which the NIGMS Council recently approved, are designed to: 1) provide equity of trainee support across programs; 2) prevent programmatic overlap; 3) align the funding strategies with the programmatic goals; 4) tailor expectation of outcomes, support mechanisms, and review considerations according to the institution’s level of research activity; and 5) strengthen our ability to evaluate the success of the programs. The changes, described in more detail in the recent Videocast of the Council Open Session, will impact the Initiative for Maximizing Student Development (IMSD), the Research Initiative for Scientific Enhancement (RISE) program, and the Maximizing Access to Research Careers – Undergraduate Student Training in Academic Research (MARC U-STAR) programs. We don’t anticipate any immediate changes to our Postbaccalaureate Research Education Program (PREP). Possible adjustments to the Bridges to the Baccalaureate and Bridges to the Doctorate programs are currently under discussion.
NIGMS has a longstanding commitment to train the next generation of biomedical scientists and support the training of students from diverse backgrounds, including groups underrepresented in biomedical research, through fellowships, career development grants, and institutional training and student development programs. These programs, and other efforts, have contributed to a substantial increase in the talent pool of well-trained biomedical Ph.D.s from historically underrepresented racial and ethnic groups. However, increasing evidence shows that transitions of these talented scientists from postdoctoral training into independent faculty positions at research-intensive institutions is a key point at which they exit the NIH-funded research workforce. Similarly, women have earned a majority of biomedical Ph.D.s since 2008 but approximately one-third of NIH-funded principal investigators are women.
We have undertaken a number of efforts to facilitate the career transitions of postdoctoral scientists from diverse groups into the professoriate including Institutional Research and Academic Career Development Awards and research supplements to promote diversity in health-related research and re-entry into biomedical research careers. Additionally, we administer the NIH Common Fund’s National Research Mentoring Network, a nationwide consortium of biomedical professionals and institutions collaborating to provide biomedical trainees from all backgrounds and at all levels with evidence-based mentorship and professional development programs. While these efforts have supported the development of highly-trained biomedical scientists who have the necessary knowledge and skills to pursue independent biomedical research careers, we need additional strategies to promote transitions to independent faculty positions at research-intensive institutions.
We’re hosting a webinar for students and fellows interested in the PRAT Program for the October 3 receipt date:
Wednesday, June 20, 1:30-2:30 p.m. ET
PRAT is a competitive three-year fellowship program that prepares trainees for leadership positions in biomedical careers. Training includes a mentored laboratory research experience and intensive career and leadership development activities. PRAT fellows conduct research in laboratories in the NIH Intramural Research Program (IRP) in basic biomedical research areas within the NIGMS mission. These areas include, but are not limited to, biological chemistry, biophysics, bioinformatics, cellular and molecular biology, computational biosciences, developmental biology, genetics, immunology, neuroscience, pharmacology, physiology, and technology development.
Applicants can be graduate students considering postdoctoral research opportunities or fellows with no more than two years of postdoctoral research experience by the time of appointment to the PRAT program (late summer 2019). All applications require connecting with an investigator in the NIH IRP in advance of writing the application.
To access the webinar, visit the WebEx meeting page (no longer available) and enter the meeting number (access code) 625 876 209 and the password MjRSPSrH. You can also attend by phone by calling 650-479-3208. Slides will be posted on the PRAT website following the event.
NIGMS Staff and PRAT Fellows Participating in June 20 Webinar:
Kenneth Gibbs, Director, PRAT Program
Mercedes Rubio, Program Officer, PRAT Program
Amy Elliott, PRAT Fellow
Sam Golden, PRAT Fellow
Laura Corrales-Diaz Pomatto, PRAT Fellow
We look forward to talking with you about the PRAT Program.