Year: 2019

Funding Opportunity: NIGMS National and Regional Resources

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UPDATE: The slides [PDF, 296KB] from the National and Regional Resources Webinar have been posted.

Research resources provide access to technologies, methods, and expertise that are not generally available to individual laboratories. Large-scale research resources can significantly broaden access to cutting-edge technologies and can achieve economies of scale not possible for facilities serving individual institutions.

We have just published a new funding opportunity announcement (FOA) to support national and regional (multistate) resources for biomedical research that will provide access to state-of-the-art facilities, equipment, technologies, research tools, and software to many users. We expect the impact of these resources and the number of users to be on a similar scale to what is achieved by synchrotron beamlines and cryo-electron microscopy centers.

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Funding Opportunity: Diversity Program Consortium Dissemination and Translation Awards (DPC DaTA) and Webinar

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UPDATE: The slides [PDF, 590KB] from the DPC DaTA Webinar have been posted.

On behalf of the NIH Common Fund, we’ve just released a new funding opportunity announcement soliciting applications for the Diversity Program Consortium Dissemination and Translation Awards (DPC DaTA) (U01).

This initiative is designed to broaden the DPC’s national impact. It provides an opportunity for institutions not currently part of the DPC to apply for funding to employ the consortium’s experimental methods to understand the effectiveness of biomedical research training, mentoring, or research capacity building interventions.

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NIGMS Statement in Support of Diverse and Inclusive Meetings and Conferences

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On June 12, NIH Director Francis Collins announced that he will not take part in conferences or meetings in which “attention to inclusiveness is not evident in the agenda.” In keeping with this announcement, all NIGMS staff, including leadership, program and scientific review officers, grants management specialists, and others, will only attend meetings and conferences where the organizers have shown a strong commitment to diversity and inclusion in their selection of chairs, speakers, and panelists. NIGMS has a long-standing mission to promote diversity in the scientific enterprise. Helping to ensure that the organizers of scientific conferences and meetings plan diverse and inclusive agendas will further our goal of developing the most creative, vibrant, and productive biomedical research workforce possible.

Funding Opportunity: Sponsored Programs Administration Development (SPAD) Program and Webinar

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UPDATE: The slides [PDF, 350KB] from the SPAD Webinar have been posted.

We’ve just released a new funding opportunity announcement (FOA) soliciting applications for the Diversity Program Consortium’s Sponsored Programs Administration Development (SPAD) Program (UC2).  

A primary goal of the program is to enhance faculty and student participation in biomedical research and research training programs. These programs include undergraduate research programs, Academic Research Enhancement Awards (R15), and Support of Competitive Research (SC1, SC2, SC3), among others. Funded institutions are expected to develop offices that provide services such as professional development in targeted areas (e.g., enhancing grant-writing skills), pre- and post-award services, and certification-guided training of sponsored program staff and leadership.

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Webinar for Postdoctoral Research Associate Training (PRAT) Program Applicants

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UPDATE: The slides [PDF, 1.04MB] and video Link to external web site from the PRAT Program Applicant Webinar have been posted.

We recently reissued the funding opportunity announcement (FOA) for the Postdoctoral Research Associate Training (PRAT) Program and will host a webinar for interested students and fellows:

Wednesday, June 19, 2:00-3:00 p.m. ET

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Recommendations of the NAGMS Working Group on Sepsis

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Sepsis is a serious condition that affects about 1.7 million people and causes about 270,000 deaths annually in the U.S. Because it involves multiple organ systems, it is also one of the clinical research areas supported by NIGMS. Despite decades of research, sepsis remains a poorly understood condition with limited diagnostic tools or therapeutic interventions.

Nearly a year ago, we established a working group of our Advisory Council to advise us on how best to advance sepsis research. At last week’s Council meeting, Dr. John Younger and Dr. Monica Kraft, co-chairs of the working group, presented the group’s recommendations:

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Does your application fit the scientific mission of NIGMS?

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Prospective applicants frequently ask us whether their application ideas fit within our mission. NIGMS supports basic research that increases our understanding of biological processes and lays the foundation for advances in disease diagnosis, treatment, and prevention. We also support research in some specific clinical areas that affect multiple organ systems, including anesthesia, sepsis, wound healing, and trauma. In addition, we’re committed to training the next generation of scientists, enhancing the diversity of the scientific workforce, and developing research capacity throughout the country.

Not all applications for fundamental biomedical research projects will ultimately be assigned to NIGMS.  Other NIH institutes and centers (ICs) also have strong commitments to basic research that underlie an understanding of their own particular organ systems, diseases, or treatments. Each NIH IC is different and supports distinct research areas, so it’s wise to seek advice from the program where your science best fits. Before submitting an application to NIGMS, we strongly recommend that you contact the program director whose portfolio most closely matches your area of research.

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Funding Opportunity: Methods to Improve Reproducibility of iPSC Derivation, Growth, and Differentiation

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NIGMS, along with 11 other NIH institutes and centers, is seeking Small Business Innovation Research (SBIR) applications to develop methods that improve the reproducibility of human induced pluripotent stem cell (iPSC) derivation, growth, and differentiation (RFA-GM-19-001). Human iPSCs are mature cells that have been reprogrammed to an embryonic stem cell-like state and are able to differentiate into any cell type in the body. iPSCs are increasingly important research systems with a wide variety of applications, including studies of human development, tissue regeneration and repair, disease processes, and the development of new therapeutics. iPSCs and other regenerative technologies also have potential to transform clinical practice by creating living, functional tissues to repair or replace tissues or organs lost due to age, disease, damage, or congenital defects. Realizing the full potential of human iPSCs for both research and clinical practice has been limited by the significant variability in reprogramming efficiency, differentiation potential, and cell growth and stability. This funding opportunity announcement (FOA) will support SBIR projects to develop novel, reliable, and cost-effective methods to standardize and increase the utility and reproducibility of iPSCs at all stages, from their derivation to their research and clinical applications.

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