Author: Mary Ann Wu

Headshot of Mary Ann Wu.

Mary Ann administered structural biology grants in support of research resources and biomedical technology development until leaving NIGMS for the NIH Office of the Director in November 2023.

Posts by Mary Ann Wu

NIGMS Administrative Supplements for Equipment


UPDATE: The first bullet under the R01, R35, and R37 heading has been expanded to indicate the supplement can’t exceed the direct costs of the parent award.

We’re offering administrative supplements for equipment to select NIGMS-funded research projects, resources, centers, and core facilities. Funds are intended for the purchase of needed equipment that will enhance user access to the resource and/or the impact of the parent grant. The application deadline is March 1.

R01, R35, and R37 grantees:

  • Funds are available for the purchase of single equipment systems with requested direct costs up to $250,000, as long as it doesn’t exceed the direct costs of the parent award.
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Equipment Funding Opportunities for NIGMS Research


NIGMS recognizes the need to provide support to grantees for equipment, particularly to replace essential instrumentation that breaks down, or to expand into rapidly growing research areas. As an example, advances in cryo-electron microscopy (cryo-EM) detectors, microscopes, and methods have made acquisition of atomic resolution structural data a reality, and investigators need these to prepare viable specimens and process data in their home labs to successfully utilize cryo-EM data collection resources elsewhere.

We’re pleased to share with you recent funding opportunities for equipment support.

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Funding Opportunity to Develop Cryo-EM Online Instructional Materials

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In addition to the currently active funding opportunity announcement (FOA) for national cryo-electron microscopy (cryo-EM) centers, NIH has issued an FOA for research education program grants for cryo-EM curriculum development. Both FOAs are part of a new NIH/Office of Strategic Coordination Common Fund program being led by NIGMS and the National Eye Institute (NEI).

The research education grants will support investigator-driven development and dissemination of online educational materials, such as video-based tutorials, novel self-paced learning approaches and computer-based educational tools, to instruct biomedical researchers in the application of cryo-EM techniques, theory and analysis. Techniques include cryo-EM single particle analysis and cryo-electron tomography. Applications are due by July 25, 2017, with optional letters of intent due one month earlier.

If you have questions about the research education grants announcement, please email NEI’s Houmam Araj or call him at 301-451-2020. Please also help us get the word out by letting your community know of this opportunity.

Funding Opportunity for National Cryo-EM Centers


NIGMS and the National Eye Institute (NEI) are leading a new NIH Common Fund program: Transformative High Resolution Cryo-Electron Microscopy. This initiative will establish national service centers to increase research capacity for molecular structure determination by high resolution cryo-electron microscopy (cryo-EM). The centers will provide access to state-of-the-art equipment, technical support and cross-training for the production and analysis of high resolution cryo-EM data. An open application process will offer equal-opportunity access to researchers nationwide.

The NIH Common Fund recently issued a funding opportunity announcement for these national centers. The application deadline is June 30, 2017, with optional letters of intent due by May 30. For more information about the cryo-EM centers announcement, please email me. Please also help us get the word out by letting your community know of this opportunity.