Category: Funding Opportunities

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Funding Opportunities, Requests for Information Issued

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You may be interested in the following funding opportunity announcements and NIH requests for information:

Funding Opportunity Announcements

NIH Requests for Information

Funding Opportunity Announcements

Modeling Social Behavior (R01)
(RFA-GM-13-006)

Purpose: Develop and test innovative theories and computational, mathematical or engineering approaches to deepen understanding of complex social behavior
Letter of intent due date: March 3, 2012
Application due date: April 3, 2012
NIGMS contact: Stephen Marcus, 301-451-6446

Competing Revisions for Macromolecular Interactions in Cells (R01)
(RFA-GM-13-003)

Purpose: Extend the scope and capabilities of currently funded investigations on macromolecular interactions and their relationship to function in cells
Letter of intent due dates: February 26, 2012; September 18, 2012
Application due dates: March 26, 2012; October 18, 2012
NIGMS contact: James Deatherage, 301-594-0828

Jointly Sponsored Ruth L. Kirschstein National Research Service Award Institutional Predoctoral Training Program in the Neurosciences (T32)
(PAR-12-084)

Purpose: Prepare predoctoral students for independent research careers in the neurosciences
Letter of intent due dates: April 25, 2012; April 25, 2013; April 25, 2014
Application due dates: May 25, 2012; May 25, 2013; May 25, 2014
NIGMS contact: Alison Cole, 301-594-3827

PHS 2012-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
(PA-12-088)

Purpose: Submit Small Business Innovation Research (SBIR) Phase I, Phase II, Fast-Track and Phase IIB competing renewal grant applications
Application due dates: Standard dates apply
NIGMS contact: Scott Somers, 301-594-3827

PHS 2012-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])
(PA-12-089)

Purpose: Submit Small Business Technology Transfer (STTR) Phase I, Phase II, Fast-Track and Phase II competing renewal grant applications
Application due dates: Standard dates apply
NIGMS contact: Scott Somers, 301-594-3827

Resource Access for the Bridging Interventional Development Gaps Program (X01)
(PAR-12-092)

Purpose: Acquire access to government-funded contract resources needed for the preclinical development of therapeutic agents
Application due date: April 3, 2012
NIH contact: Tony Jackson, 301-594-4660

NIH Requests for Information

Request for Information (RFI): Input into the Deliberations of the Advisory Committee to the NIH Director Working Group on Diversity in the Biomedical Research Workforce
(NOT-OD-12-031)

Purpose: Provide input to a working group charged with examining diversity in the biomedical research workforce and providing recommendations on ways to enhance diversity throughout various research career stages, particularly with regard to underrepresented minorities, persons with disabilities and persons from disadvantaged backgrounds
Response due date: February 24, 2012

Request for Information (RFI): Input into the Deliberations of the Advisory Committee to the NIH Director Working Group on Data and Informatics
(NOT-OD-12-032)

Purpose: Provide input to a working group charged with investigating the management, integration and analysis of large biomedical datasets
Response due date: March 12, 2012

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Addressing Additional Review Criteria Questions for AREA Applications

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Of all the institutes and centers at NIH, NIGMS receives the most Academic Research Enhancement Award (AREA, R15) applications and funds the most AREA grants. This is probably because the faculty and students at eligible institutions, which have not been major recipients of NIH research grant funds, typically focus on basic research using model organisms and systems.

As Sally Rockey of the NIH Office of Extramural Research has noted, the new AREA funding opportunity announcement includes additional questions reviewers are expected to address that are related to the program’s goals of supporting meritorious research, strengthening the research environment of eligible institutions and exposing students to significant research.

With the next AREA application deadline coming up on February 25, I’d like to point out how and where applicants might address the new review considerations.

SIGNIFICANCE: If funded, will the AREA award have a substantial effect on the school/academic component in terms of strengthening the research environment and exposing students to research? Include a summary discussion at the end of the Research Plan, but provide most of the information on lab space, required equipment and facilities, and the availability of students to participate in the proposed research in the Resource page of the application. You and your institution should also include a description of the current research environment and of students who have continued in the biomedical sciences. In the Significance section as well as at the end of the Research Plan, discuss how the potential R15 support would enhance the research environment and increase the number of students exposed to meritorious research. Please remember that the research proposed should be significant, have an impact on the field and be well justified.

INVESTIGATOR: Do the investigators have suitable experience in supervising students in research? Take advantage of the Biosketch Personal Statement to provide specific information about current and former students participating in your research projects. Highlight publications with student co-authors in the Biosketch, and describe the role of students to be supported on the research project and which aim they will help with in the Budget/Personnel Justification and in the timeline at the end of the Research Plan.

APPROACH: Does the application provide sufficient evidence that the project can stimulate the interests of students so that they consider a career in the biomedical or behavioral sciences? As noted above, address this question in the Resource page and the Biosketch Personal Statement with a discussion of students who have previously worked on aspects of the research and who plan to pursue scientific careers. At the end of the Research Plan, I highly recommend including a list of students and a timeline for what each of them would be doing and what research question or approaches they would be exposed to during the R15 support period.

ENVIRONMENT: Does the application demonstrate the likely availability of well-qualified students to participate in the research project? Address this question in both the Resource page and the Biosketch Personal Statement by discussing your record of recruiting interested students who are excited about doing research and helping you accomplish your specific aims. Does the application provide sufficient evidence that students have in the past or are likely to pursue careers in the biomedical or behavioral sciences? As indicated above, with assistance from your institution, use the Resource page to provide a description of students who have majored in the biomedical sciences and who have gone on to graduate or medical school or other biomedical science careers. Use the Biosketch Personal Statement to describe students you have supervised.

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Four Funding Opportunities Issued

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You may be interested in the following recently issued funding opportunity announcements:

Postbaccalaureate Research Education Program (PREP) (R25)
(PAR-12-056)

Purpose: Prepare recent baccalaureate science graduates from diverse backgrounds for Ph.D. or M.D.-Ph.D. degrees in biomedical and behavioral sciences
Application due date: February 24, 2012
NIGMS contact: Michael Bender, 301-594-0943

Solicitation of Assays for High Throughput Screening (HTS) to Discover Chemical Probes (R01)
(PAR-12-058)

and

Solicitation of Assays for High Throughput Screening (HTS) to Discover Chemical Probes (R21)
(PAR-12-059)

Purpose: Form collaborations with an academic, nonprofit or commercial high throughput screening (HTS) facility that has the expertise and experience to implement an HTS-ready assay to develop and discover small-molecule chemical probes
Letter of intent due date: 30 days prior to the anticipated application due date
Application due date: Standard dates apply
NIGMS contact: Miles Fabian, 301-594-3827

Solicitation of Validated Hits for the Discovery of in vivo Chemical Probes (R01)
(PAR-12-060)

Purpose: Discover and develop novel in vivo chemical probes for potential use in studying diseases
Letter of intent due date: 30 days prior to the anticipated application due date
Application due date: Standard dates apply
NIGMS contact: Miles Fabian, 301-594-3827

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Two New Funding Opportunities Issued

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You may be interested in the following recently issued funding opportunity announcements:

New Methods for Understanding the Functional Role of Human DNA Sequence Variants in Complex Phenotypes (R01)
(RFA-GM-13-002)

Purpose: Use experimental and/or computational methods to determine the functional relevance of human DNA sequence variants
Letter of intent due date: January 17, 2012
Application due date: February 17, 2012
NIGMS contact: Donna Krasnewich, 301-594-0943

Mentored Research Scientist Development Award in Metabolomics (K01)
(RFA-RM-11-017)

Purpose: Pursue intensive research training in the field of metabolomics
Application due date: January 31, 2012
NIGMS contact: Richard Okita, 301-594-3827

This funding opportunity announcement (FOA) was issued by the NIH Common Fund but will be administered by NIGMS. For other recently issued Common Fund FOAs, including several focused on single cell biology, see the NIH Guide.

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NIGMS Research Supplement Program to Promote Diversity Continues

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As we begin the new fiscal year, I’ve received questions about whether NIGMS plans to continue its diversity supplement program. The answer is a definite yes. We remain committed to this program, which addresses the important goal of increasing the diversity of the biomedical and behavioral workforce by providing supplemental support for research experiences and mentorship for students and fellows at a range of levels, from high school through postdoctoral training.

Diversity supplement requests may be submitted throughout the year and are reviewed within NIGMS on a rolling basis. Applicants should be aware that the program is competitive and we only fund meritorious applications that meet the program’s goals.

For more information, visit our diversity supplement Web site, which we have recently updated to reinforce the NIGMS philosophy for the program and to clarify eligibility and application requirements. In addition, we have added frequently asked questions and answers. Before submitting an application, I suggest that you contact either your program director or me at zatzm@nigms.nih.gov or 301-594-3833.

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NIGMS-Related Funding Opportunities

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You may be interested in the following funding opportunities that were recently published in the NIH Guide:

Collaborations with National Centers for Biomedical Computing (R01)
(PAR-12-001)

Purpose: Use computational tools and biological and behavioral application drivers of the funded National Centers for Biomedical Computing as a foundation for building a biomedical computing environment
Application due date: Standard dates apply
NIGMS contact: Peter Lyster, 301-451-6446
More info: National Centers for Biomedical Computing Web site (no longer available)

Dynamics of Host-Associated Microbial Communities (R01)
(RFA-GM-13-001)

Purpose: Reveal basic principles and mechanisms that govern the symbiotic systems dynamics of host-associated microbial communities through genetic, physiological and ecological studies
Letter of intent due date: December 13, 2011
Application due date: January 13, 2012
NIGMS contact: Shiva Singh, 301-594-3900

Short Courses on Mathematical, Statistical, and Computational Tools for Studying Biological Systems (R25)
(PA-11-351)

Purpose: Conduct workshops and short courses to improve integration of mathematical, statistical and computational approaches into biological and/or behavioral research
Letter of intent due date: 30 days before application due date
Application due date: Standard dates apply
NIGMS contact: Irene Eckstrand, 301-594-0943

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NIGMS-Related Funding Opportunities

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You may be interested in the following funding opportunities that were recently published in the NIH Guide:

NIH Director’s Transformative Research Awards (R01)
(RFA-RM-11-006)

Purpose: Support exceptionally innovative, high-risk, unconventional research
Letter of intent due date: December 12, 2011
Application due date: January 12, 2012
NIGMS contact: Laurie Tompkins, 301-594-0943
NIH contact: Ravi Basavappa, 301-435-7204
More info: This is an NIH Common Fund program; it replaces the NIGMS EUREKA and the NIH Director’s Transformative Research Project (TR01) initiatives

Mechanistic Pathways Linking Psychosocial Stress and Behavior (R01)
(RFA-HL-12-037)

Purpose: Investigate basic psychological, social and environmental mechanisms and processes linking psychosocial stressors and behaviors that may ultimately impact biological function, health and disease
Letter of intent due date: November 19, 2011
Application due date: December 19, 2011
NIGMS contact: Stephen Marcus, 301-451-6446
NHLBI contact: Catherine Stoney, 301-435-6670
More info: Issued by the NIH Basic Behavioral and Social Sciences Opportunity Network (OppNet)

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Collaborative Science Supplement Requests Due in January

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Do unexpected results from your NIGMS-funded R01 or R37 project have you thinking about your research in a different way, or is there a new approach that will greatly advance the aims of your studies? Will you need a collaborator with appropriate expertise to proceed?

If you answered “yes” to these questions, you might consider applying for an administrative supplement for collaborative science (SCS). Now in its 4th year, the SCS program enables new collaborations that were not initially planned and therefore are not supported by the parent grant. Grants must be actively funded through at least July 31, 2013, to be eligible for the next submission deadline of January 15, 2012.

To be sure that your proposal is appropriate for this program, please read the NIH Guide notice, review the program description (no longer available) and discuss your plans with your NIGMS program director. For general questions about the program, e-mail me or Marion Zatz.

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Announcing Funding Opportunities and Research Administration News

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We’re trying something new! To keep you posted on funding opportunities, we’ll provide a digest of NIGMS-related announcements soon after they appear in the NIH Guide for Grants and Contracts, typically every 1 to 2 weeks. (You also can subscribe to get a weekly list of all NIH Guide announcements.)

Similarly, we plan to post monthly digests of relevant highlights from the NIH Office of Extramural Research blog.

Here is the first digest of funding opportunities. Please let me know if you do or don’t like this format or if you have suggestions for ways to improve its usefulness to you.

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You may be interested in the following funding opportunities that were recently published in the NIH Guide:

NIGMS Centers for HIV/AIDS-Related Structural Biology (P50)

RFA-GM-12-003
Purpose: Structure determination and dynamic characterization of macromolecular complexes among and between components of HIV and the components of host cells
Letter of intent due date: December 7, 2011
Application due date: January 6, 2012
NIGMS contact: Michael Sakalian, 301-594-0828
More info: http://www.nigms.nih.gov/Research/SpecificAreas/
AIDSStructuralBiology/

Lab to Marketplace: Tools for Biomedical and Behavioral Research (SBIR [R43/R44])

PA-11-335
Purpose: Translation of technologies for biomedical or behavioral research from academic and other non-small business research sectors to the marketplace
Application due date: Standard dates apply
NIGMS contact: Scott Somers, 301-594-3827
More info: http://www.nigms.nih.gov/Research/Mechanisms/Pages/SBIR.aspx

Development of Novel and Emerging Technologies for the Accurate Detection and Diagnosis of Polymicrobial Infections in Biomedical Laboratory Animal Models (SBIR [R43/R44]), (STTR [R41/R42])

SBIR: PA-11-340; STTR: PA-11-341
Purpose: Rapid and sensitive detection of infectious agents as a key requirement for microbial identification in laboratory animal models
Application due date: Standard dates apply
NIGMS contact: Stefan Maas, 301-594-0943
More info: http://www.nigms.nih.gov/Research/Mechanisms/Pages/SBIR.aspx, http://www.nigms.nih.gov/Research/Mechanisms/Pages/STTR.aspx