Category: Funding Opportunities

Posted on

New Program Announcements for Biomedical Technology Research Resources

by
0 comments

I would like to call your attention to two program announcements recently published in the NIH Guide:

These announcements provide updated instructions for both pre-applications and full applications for Biomedical Technology Research Resource (BTRR) grants. The BTRR program supports development and dissemination of advanced technologies that enable biomedical research The BTRR centers create a wide range of technologies and work with thousands of NIH-supported investigators each year.

The X02 pre-application is strongly recommended. The pre-application provides an opportunity for prospective applicants to receive feedback from both peer reviewers and NIGMS program staff as they formulate their plans for a complex, lengthy proposal for a P41 grant.

Following an evaluation in 2016, we have revised the BTRR program, while preserving the fundamental mission of developing and providing access to advanced technologies. Susan Gregurick, director of our Biomedical Technology, Bioinformatics, and Computational Biology Division, presented on the evaluation and proposed program changes at the September 2016 NIGMS Advisory Council meeting.

Revisions to the program have changed the structure of a BTRR to give the investigators who run the centers more flexibility in how technologies are shared with the community. A new feature, “Technology Development Partnerships,” will enable centers to rapidly adopt and incorporate emerging technologies developed elsewhere that advance a BTRR’s overall mission, rather than focus entirely on technologies developed “in-house.”

The program also will provide investigators with greater flexibility to tailor a center’s approach to technology innovation, user access and training, and dissemination according to the specific technologies being developed and communities being served. At the same time, the program will place a greater emphasis on actively moving technologies out of the BTRR and into the wider community as quickly as possible. We anticipate that most BTRR centers will not be funded beyond three cycles (15 years), and we will require investigators involved with this program to formulate a sustainability plan for their research resources.

The submission date for the first round of X02 pre-applications is August 15, 2017. Future submission dates will follow a regular schedule, occurring twice per year in March and July. That timing allows nine months from submission of the X02 until the anticipated submission of a resulting full application in January or May, respectively.

The next submission date for full applications for a P41 BTRR is September 25, 2017. This is the only submission date for funding in Fiscal Year 2018. In future years, applications will be accepted twice per year, in January and May, with no September submission. To improve consistency in the review of competing applications, the NIH Center for Scientific Review will convene a special study section to review all NIGMS P41 BTRR applications together. There will be no site visits.

NIGMS also supports technology development through several other programs. To help investigators determine which technology development program is right for their project, we’ve posted a decision tree on the NIGMS website. It includes descriptions of the programs designed to support specific stages of technology development.

I welcome questions or comments about these FOAs or our technology development programs in general.

Posted on

FOA for Clinical Trial Planning Grants

by
0 comments

NIGMS supports research in specific clinical areas that affect multiple organ systems. We recently reissued the funding opportunity announcement for clinical trial planning grants of high relevance to the NIGMS mission. We strongly encourage investigators to apply for a planning grant before submitting an application for a full clinical trial in one of the clinical areas that NIGMS supports. The next application deadline is August 7, with optional letters of intent due by July 7.

If you’re interested in applying for a clinical trial planning grant, we recommend that you consult with the appropriate NIGMS program staff  before you apply to determine whether the goal of the proposed trial aligns with the NIGMS mission and scientific priorities.

For more information, see our Clinical Studies and Trials webpage, which includes links to other useful resources like the NIGMS Guidelines for Data and Safety Monitoring in Clinical Trials. In addition, please note that last year NIH announced a suite of policy changes known as Clinical Trial Stewardship Reforms that are designed to improve the clinical trial application and award process as well as the sharing of clinical trial data and results with other researchers and the public.

If you have any questions about NIGMS’ support of clinical trials, please contact me.

Posted on

Webinar and Other Resources for New MIRA ESI Funding Opportunity

by
0 comments

UPDATE: The slides from the MIRA ESI Funding Opportunity Webinar have been posted.

NIGMS recently reissued the funding opportunity announcement (FOA) for the Maximizing Investigators’ Research Award (MIRA) program for Early Stage Investigators. The first application due date is October 3, 2017. As in previous years, the purpose of this MIRA mechanism is to provide support for the program of research in the laboratory of an early stage investigator (ESI) that falls within the mission of NIGMS. Here are some important points to know if you’re considering applying to this FOA:

  • To be eligible, you must have completed your terminal research degree (or medical residency) less than 10 years ago and must not have served as the principal investigator (PI) of a substantial NIH research award, e.g., an R01, P01, U01, SC1 or DP2. If you’ve served as the PI of one or more smaller awards, such as an R00, R03, R15, R21, SC2 or SC3, you retain your ESI status and can still apply to the ESI MIRA program. A complete list of the smaller grants and awards that do not affect ESI status is available on the Office of Extramural Research webpage.
  • ESI status can be extended for qualifying reasons, including but not limited to family care responsibilities or active military service. Here’s a complete list of qualifying reasons.
  • If you submitted a MIRA application in previous years and are still eligible for this FOA (i.e., retain ESI status), you’re welcome to apply but must submit a new application rather than a resubmission. A new application may still cover the same topics you proposed previously, but must not include any specific section explicitly designated as a response to reviewers.
  • If offered a MIRA, you must devote at least 51% of your time available for research to the award; however, note that taking less than 51% salary for the PI is allowed and in no case should more than 51% be requested.
  • Unlike previous rounds, you may have an NIGMS R01 application and a MIRA application under review at the same time. Should both applications score well enough to be considered for funding, you will be required to withdraw one or the other.
  • Applications that don’t fall within NIGMS’ mission will be returned without review, so be sure to contact me or the program director whose scientific area is closest to yours to discuss your proposal while in the planning stages!

These and many other topics related to the MIRA ESI FOA are covered in detail in a newly-released set of frequently asked questions.

We’ll also be hosting a webinar to discuss the FOA (no longer available) and answer your specific questions about the program on Monday, July 10, from 1:30-2:30 p.m. EDT. The site is compatible with mobile devices. For an audio-only presentation, call 1-888-989-5313 and enter passcode 8866047. We plan to post the archived webinar and slides on the MIRA webpage after the event.

NIH Staff Participating in July 10 Webinar

Jon Lorsch, Institute Director

Kristine Willis, Program Director

Brian Pike, Scientific Review Officer

Lisa Moeller, Grants Management Officer

Posted on

Webinar for Students and Fellows Interested in NIGMS’ Postdoctoral Research Associate (PRAT) Program

by
0 comments

UPDATE: The video and slides from the PRAT Program Webinar have been posted.

We’re hosting a webinar for potential applicants to the PRAT Program on Tuesday, March 28, from 12:00-1:30 p.m. EDT. PRAT is a three-year program providing outstanding laboratory research experiences in NIH’s Intramural Research Program (IRP), access to NIH’s extensive resources, mentorship, career development activities and networking. The program places special emphasis on training fellows in basic biomedical research areas including cell biology, biophysics, genetics, developmental biology, pharmacology, physiology, biological chemistry, computational biology, immunology, neuroscience, technology development and bioinformatics.

The next receipt date for applications is October 3, 2017.  Applicants can be graduate students considering postdoctoral research opportunities or postdoctoral fellows with no more than two years of postdoctoral research experience by the time of appointment to the PRAT program (late summer 2018). All applications require connecting with an investigator in the NIH IRP in advance of writing the application.

To attend the webinar, join the Skype meeting (link no longer available) shortly before 12:00 p.m. EDT and enter the conference ID 8368072. You can also attend by phone by calling 301-480-4255. Slides will be posted on the PRAT website following the event.

We look forward to talking with you about the PRAT Program.

NIH Staff Participating in March 28 Webinar

Jessica Faupel-Badger, Director, NIGMS PRAT Program

Kenneth Gibbs, Program Director, NIGMS

Erika Ginsburg, NCI Authorized Organization Representative/Signing Official

Posted on

Funding Opportunity to Develop Cryo-EM Online Instructional Materials

by
1 comment

In addition to the currently active funding opportunity announcement (FOA) for national cryo-electron microscopy (cryo-EM) centers, NIH has issued an FOA for research education program grants for cryo-EM curriculum development. Both FOAs are part of a new NIH/Office of Strategic Coordination Common Fund program being led by NIGMS and the National Eye Institute (NEI).

The research education grants will support investigator-driven development and dissemination of online educational materials, such as video-based tutorials, novel self-paced learning approaches and computer-based educational tools, to instruct biomedical researchers in the application of cryo-EM techniques, theory and analysis. Techniques include cryo-EM single particle analysis and cryo-electron tomography. Applications are due by July 25, 2017, with optional letters of intent due one month earlier.

If you have questions about the research education grants announcement, please email NEI’s Houmam Araj or call him at 301-451-2020. Please also help us get the word out by letting your community know of this opportunity.

Posted on

Webinar for RISE Program Applicants

by and
1 comment

UPDATE: The slides from the RISE Program Applicants Webinar have been posted.

If you’re preparing an institutional RISE grant application, you might have questions about the funding opportunity announcement and data tables required for the upcoming May 25 receipt date. We’ll be available to discuss these topics during a webinar on Thursday, April 6, from 2:00-4:00 p.m. EDT. You may send questions before the webinar or post them in the chat box during the event.

To access the webinar, visit the WebEx Meeting page (link no longer available) and enter meeting number 624 498 694 and the password “RISE2017.” If you are unable to attend online, you can join by phone by calling 1-877-668-4493 from anywhere in the United States or Canada and entering the meeting number above.

We look forward to talking to you about the RISE program.

NIGMS Staff Participating in April 6 Webinar

Division of Training, Workforce Development, and Diversity:

Anissa Brown, Program Director

Luis Cubano, Program Director

Shiva Singh, Undergraduate and Predoctoral Training Branch Chief

Office of Scientific Review:

Rebecca Johnson, Scientific Review Officer

Division of Extramural Activities:

Susan South, Grants Management Specialist

Posted on

Webinar for MARC U-STAR Program Applicants

by
0 comments

UPDATE: The slides from the MARC U-STAR program applicants Webinar have been posted.

If you’re preparing an institutional MARC U-STAR grant application, you might have questions about the funding opportunity announcement and data tables required for the upcoming May 25 receipt date. We’ll be available to discuss these topics during a webinar on Wednesday, March 22, from 2:00-3:30 p.m. EDT. You may send questions to me before the webinar or post them in the chat box during the event.

To access the webinar, visit the WebEx Meeting page (link no longer available) and enter meeting number 624 460 843 and the password “NIGMS.” If you are unable to attend online, you can join by phone by calling 1-877-668-4493 from anywhere in the United States or Canada and entering the meeting number above.

We look forward to talking to you about the MARC U-STAR program.

NIGMS Staff Participating in March 22 Webinar

Division of Training, Workforce Development, and Diversity:

Sailaja Koduri, Program Director

Luis Cubano, Program Director

Shiva Singh, Undergraduate and Predoctoral Training Branch Chief

Office of Scientific Review:

Rebecca Johnson, Scientific Review Officer

Division of Extramural Activities:

Lori Burge, Grants Management Officer

Posted on

Funding Opportunity for National Cryo-EM Centers

by
0 comments

NIGMS and the National Eye Institute (NEI) are leading a new NIH Common Fund program: Transformative High Resolution Cryo-Electron Microscopy. This initiative will establish national service centers to increase research capacity for molecular structure determination by high resolution cryo-electron microscopy (cryo-EM). The centers will provide access to state-of-the-art equipment, technical support and cross-training for the production and analysis of high resolution cryo-EM data. An open application process will offer equal-opportunity access to researchers nationwide.

The NIH Common Fund recently issued a funding opportunity announcement for these national centers. The application deadline is June 30, 2017, with optional letters of intent due by May 30. For more information about the cryo-EM centers announcement, please email me. Please also help us get the word out by letting your community know of this opportunity.

Posted on

MIRA Program Expands Eligibility with New FOA

by
0 comments

UPDATE: The January 31 Webinar has been posted.

A new funding opportunity announcement (FOA) for the Maximizing Investigators’ Research Award (MIRA) program will expand eligibility to include all grantees who have at least one NIGMS R01-equivalent award (R01, R37, DP2 or SC1) due for renewal in the current or next fiscal year. Investigators with two or more NIGMS grants are eligible if at least one of their grants is up for renewal during this time period. The deadline for the first round of applications is May 17, 2017, with the earliest award date of May 2018. There will be two receipt dates in 2018 and 2019: January 17 and May 17.

The advantages of a MIRA for NIGMS grantees are that awards are for five years, provide support for an investigator’s overall program of research within the NIGMS mission, and offer greater funding stability and research flexibility while reducing the administrative burden.

In transitioning from a pilot to an ongoing grant mechanism, we have made some minor changes to the MIRA program. For example, the NIH Center for Scientific Review will review MIRA applications from established investigators. For more details, please read the FOA and the frequently asked questions. We also have posted a simple process to determine 2017 eligibility. I strongly encourage those who intend to apply to discuss their plans with their NIGMS program director.

We’ll hold a webinar to discuss the FOA (link no longer available) and answer questions about the program on Tuesday, January 31, from 2-3 p.m. EST. We plan to post the archived webinar and slides on the MIRA webpage after the event.

For additional information, please email me, or call me at 301-594-3827—and watch the Feedback Loop for updates, including an anticipated MIRA FOA for early stage investigators.

Posted on

New NIGMS Technology Development Program Announcements

by and
0 comments

We would like to tell you about two new technology development funding opportunity announcements (FOAs) recently published in the NIH Guide. We previously wrote about the approval of these programs by our Advisory Council. They are part of an ongoing effort to facilitate early stage, investigator-initiated work to create or improve tools for biomedical research. We think the two FOAs briefly described below will stimulate early stage technology research and development by allowing scientists to focus on making the technology work before they begin to apply those tools to biomedical research questions.

Exploratory Research for Technology Development (PAR-17-046): This program will support modest 2-year R21 grants to develop a new technology or radically improve an existing one. Projects will be high-risk and have no preliminary data. The proposed technology should be justified by a significant biomedical research need, but the proposal should not include the application of the technology to a biomedical problem—it should focus on technology development.

Focused Technology Research and Development (PAR-17-045): This program will support R01 grants that are entirely focused on the development of an emerging technology with a strong potential to impact biomedical research. The program will not allow inclusion of a significant biomedical research problem because the technology will not be ready for that until the project is over. These grants will be renewable only once.

The deadline for the first round of applications is February 16, 2017.

To help investigators determine which technology development program is right for their project, we’ve posted a decision tree on the NIGMS website. It includes descriptions of the programs designed to support all stages of technology development.

We welcome questions or comments about these FOAs or our technology development programs in general.