NIGMS Administrative Supplements for Equipment

UPDATE: For additional information, see the Notice of Availability of Administrative Supplements for Equipment Purchases for NIGMS Awardees, NOT-GM-18-022. Applications are due May 31.

NIGMS is offering administrative supplements of between $50,000 and $250,000 for the well-justified purchase of single pieces of equipment. In past years, we issued separate funding announcements (PA-15-089 and PA-16-125) for this purpose. This year, however, we will accept requests for equipment supplements from Principal Investigators (PIs) who hold NIGMS R01, R35, R37, or R15 awards under PA-18-591, Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional).

Eligible investigators are strongly encouraged to discuss potential requests with their program directors before submitting applications. Two or more NIGMS grantees at the same institution may submit separate but cross-referenced requests, where the funds requested reflect the actual proportion of the time that the shared equipment would be used by each PI. However, under no circumstances may a joint request exceed $400,000 in direct costs. The requested supplemental budget cannot exceed the total year direct cost amount of the parent award. PIs may not request future year funds. NIGMS strongly encourages investigators to seek matching funds from their institutions or elsewhere, and to ensure that follow-up expenses (such as maintenance contracts) will be covered from other available funds. Institutional contributions and commitment will be factored into funding decisions.

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Reviewers Will Be Ready for the New Predoctoral T32 FOA

The first receipt date for predoctoral T32 applications in response to NIGMS Funding Opportunity Announcement (FOA) PAR-17-341 is fast approaching—May 25, 2018. While a wealth of information is already available regarding the intent and requirements of this new FOA, including on our NRSA Institutional Predoctoral Training Grants website and a recent Feedback Loop post, we want to reassure prospective applicants that we are also actively preparing for the review of these applications.

All predoctoral T32 applications submitted to NIGMS are currently reviewed by two in-house standing review committees, TWD-A and TWD-B, and this will continue for applications submitted under the new FOA. However, we are mindful that reviewing these applications requires different expectations and considerations, and that reviewers must accordingly be prepared for them. To this end, scientific review officers in our Office of Scientific Review are working closely with program staff in the Division of Training, Workforce Development, and Diversity to revise the materials and resources currently used to orient review committee members to ensure they understand and address the new review criteria appropriately. We are also exploring options to add expertise to the committees in aspects of the FOA that may be less familiar to reviewers, such as program evaluation, evidence-based approaches to teaching and mentoring, and non-academic career development. In addition, we are considering ways to bring the perspectives of community members who educate and mentor undergraduate students who go on to pursue Ph.D.s in biomedical fields, as well as of those who employ graduates of NIGMS-funded Ph.D. programs, such as representatives from the pharmaceutical and biotechnology industries. And of course, NIGMS review and program staff are available at each step, including during the review meetings, to provide guidance and reminders.
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NIGMS Transitions AREA Support to Undergraduate-Focused Institutions

NIGMS is realigning its support of the Academic Research Enhancement Award (AREA) program to focus on providing research experiences to undergraduate students in scientific areas within its mission. Accordingly, we’ve published a new undergraduate research-focused AREA funding opportunity announcement (FOA) and are discontinuing our participation in the NIH Parent AREA FOA. The undergraduate research-focused AREA FOA will allow us to continue to: 1) support small-scale meritorious research projects at institutions that do not receive substantial NIH funding (less than $6 million in total costs in 4 of the last 7 years), 2) enhance the research environment at eligible institutions, and 3) expose students to scientific research so that they consider careers in biomedical sciences. Unlike the Parent FOA, the new announcement allows NIGMS to place its emphasis specifically on undergraduate research.

This new AREA FOA limits eligibility to undergraduate student-focused institutions or academic components within an institution (e.g., School of Arts and Sciences) in which the undergraduate student enrollment is greater than the graduate student enrollment, and it excludes all types of health professional schools. Additionally, the research team must be composed primarily of undergraduate students. This FOA aligns the application instructions and review criteria with the goals of the AREA program. We expect that these clarifications will lead to applications that better fit the goals of the program and provide reviewers the tools they need to evaluate the program as designed.
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Planning to Apply for an NIGMS Established Investigator MIRA? Points to Consider

When NIGMS issued PAR-17-094, Maximizing Investigators’ Research Award (R35), in December 2016, we opened the established investigator MIRA mechanism to all NIGMS grantees whose single-PI R01-equivalent grants were set to terminate in the same or subsequent fiscal year as the MIRA application. The purpose of this post is to remind you of important points to keep in mind if you are eligible to apply for a MIRA. Before applying, we strongly encourage you to contact your program director, who can advise you on whether MIRA is the best funding program for you and can help estimate a project budget if your application does well in peer review.

Some key points to know if you are considering applying for a MIRA grant:

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Funding Opportunity for Development of Training Modules to Enhance the Rigor and Reproducibility of Biomedical Research

It’s crucial that the results of NIH-supported biomedical research are reproducible, unbiased, and properly validated. Establishment and use of rigorous and reproducible approaches require appropriate and sustained training of researchers and students. In 2014, we announced a funding opportunity to develop, pilot, and disseminate training modules to enhance data reproducibility. The products of these grants are posted on the NIGMS website as they become available, together with other relevant training modules about conducting rigorous and reproducible research.

We’ve just reissued a funding opportunity announcement (FOA) to support the development of additional training modules in three areas that build upon and extend those targeted through the previous FOA. The three new areas of emphasis are: 1) How scientific culture, organization, and incentives influence the rigor and reproducibility of biomedical research; 2) Good laboratory practices and record keeping; 3) Advanced experimental design and analysis.

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Webinar on NIGMS Institutional Predoctoral Training Grant Program in Basic Biomedical Sciences

UPDATE: The slides [PDF 1.38MB], video Link to external web site, and FAQs from the Predoctoral Training Grant (T32) webinar have been posted.

If you’re preparing an application for the NIGMS Institutional Predoctoral Training Grant (T32) program for the May 25 receipt date, don’t miss our upcoming webinar:

Monday, March 5, from 3:00-4:30 p.m. ET.

During the webinar, we’ll provide an overview of the new funding opportunity announcement and answer any questions you may have. You can send questions before the webinar or post them in the chat box during the event.

To join the webinar, visit the WebEx Meeting page (link no longer available) and enter the meeting number 627 943 381 and the password W7pyYXW4. If you are unable to attend online, you can join by phone by calling 1-650-479-3208 from anywhere in the United States or Canada and entering the meeting number above.

NIGMS Staff Participating in the March 5 Webinar:

Jon Lorsch, Director
Alison Gammie, Director, Division of Training, Workforce Development, and Diversity
Shiva Singh, Chief, Undergraduate and Predoctoral Training Branch
John Laffan and Lisa Newman, Scientific Review Officers
Lisa Moeller, Grants Management Officer

We look forward to talking to you about the NIGMS-sponsored T32 program.

The Diversity Program Consortium – Open Competitions for Phase II

We are pleased to announce that NIH Leadership has granted clearance for the second, final phase of the Diversity Program Consortium (DPC), a national program that is part of a larger, trans-NIH effort to enhance diversity in the biomedical research workforce. To accomplish this goal, the DPC takes a scientific approach to evaluating training and mentoring interventions. Two components of the second phase will be open competitions: the National Research Mentoring Network (NRMN) and the DPC Dissemination and Translation Awards (DPC-DaTA). The DPC-DaTA grants will allow sites that are not currently part of the DPC to implement sustainable training, mentoring, or research-capacity building interventions using DPC evaluation methods. NIH intends to release the DPC-DaTA FOAs in 2019.

The NRMN funding opportunity announcements (FOAs) were released on February 16, 2018. They include:

  • The Science of Mentoring and Networking (U01) (RFA-RM-18-004). Applicants may submit proposals for research projects in the following areas: 1) The Science of Mentorship, 2) Professional Networking, or 3) Navigating Critical Career Transition Points. Using randomized control trial approaches, case controls, matched pair designs, or other rigorous designs, applicants will explore their research questions and contribute to building the knowledge base to inform the scientific community about their thematic area.
  • NRMN Coordination Center (U24) (RFA-RM-18-003). One service award will be granted to develop an NRMN Coordinating Center. This Center will build upon and improve the current NRMN Administrative Core and work in conjunction with the Center for Evaluation and Coordination (CEC). It will coordinate trans-NRMN activities, and provide infrastructure and expertise surrounding data collection, storage, de-identification, and reporting.
  • NRMN Resource Center (U24) (RFA-RM-18-002). One service award will be granted for an NRMN Resource Center. This center will be analogous to the current U54 Mentorship and Networking Core and will provide a web-based mentoring tool to facilitate real-time mentor/mentee engagement. It will also oversee management of the NRMN website and serve as a platform for publicly available mentoring resources and tools.

Two components of the DPC for the second phase will be limited competitions. The Building Infrastructure Leading to Diversity (BUILD) (U54) (NOT-RM-18-005) will allow meritorious sites to complete their BUILD experiments. Review will include a focus on site-specific and consortium-wide experiments, and emphasize sustainability and dissemination. The Center for Evaluation and Coordination (CEC) (U54) (NOT-RM-18-006) will allow for uninterrupted data collection. The review will focus on the current center’s strengths and weaknesses, allowing for improvements and course corrections. Sustainability and dissemination will be emphasized.

Contact for questions? Mercedes Rubio for NRMN inquiries, Anissa Brown for BUILD inquiries, Michael Sesma for CEC inquiries, and Alison Gammie for DPC-DaTA inquiries.

Discontinuing Our Participation in the NRSA Individual Predoctoral Fellowship (Parent F31) Program

We recently issued an NIH Guide notice informing the community that we will discontinue participation in the Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) (PA-16-309). As stated in the notice, we will not accept new or resubmission applications for this program, and its subsequent reissuances, starting with the April 8, 2018, receipt date. We will continue to accept NRSA Individual Predoctoral Fellowships to Promote Diversity in Health-Related Research (F31) (PA-16-308) and NRSA Individual Predoctoral MD/PhD or Other Dual-Doctoral Degree Fellowships for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (F30) (PA-16-306). This decision does not affect those F31 (parent) applicants who have already received an award from NIGMS or whose applications have already been received by NIH and have been reviewed or are currently pending review.

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New Area for NIGMS Predoctoral Training

NIGMS has a longstanding commitment to graduate training and has for many years supported research training in 11 broad areas of basic biomedical science, including Behavioral-Biomedical Sciences Interface; Bioinformatics and Computational Biology; Biostatistics; Biotechnology; Cellular, Biochemical, and Molecular Sciences; Chemistry-Biology Interface; Genetics; Molecular Biophysics; Molecular Medicine; Pharmacological Sciences; and Systems and Integrative Biology.

With publication of the NIGMS’ new predoctoral training grant funding opportunity announcement, the list now includes Transdisciplinary Basic Biomedical Sciences. This new area is designed to broaden the scope of disciplines supported by an NIGMS training grant and increase the geographical distribution of institutions that might apply.

The transdisciplinary area is open only to a) institutions that currently do not have an NIGMS-funded institutional predoctoral T32 training program in any of the basic biomedical science disciplines listed above (with the exception of Behavioral-Biomedical Sciences Interface or Biostatistics), or b) institutions with current NIGMS-funded predoctoral T32 training programs that propose to merge two or more of their existing NIGMS-funded predoctoral training programs into a single program. Training supported in this area is expected to be broadly-based and multidisciplinary in nature and may be covered by the other NIGMS-supported areas of basic biomedical science disciplines, or may include other emerging area(s) within the NIGMS mission.

Applications for the Transdisciplinary Basic Biomedical Sciences area will be accepted for the May 25, 2018, receipt date and thereafter.

We welcome your comments and questions—they can be posted here, emailed to me, or you may call 301-594-3900.

Webinar for Regional Technology Transfer Accelerator Hubs for IDeA States FOA

UPDATE: The slides and video Exit icon from the Regional Technology Accelerator Hubs webinar have been posted.

If you or your institution are considering applying for our Regional Technology Transfer Accelerator Hubs for IDeA States (STTR) funding opportunity—a new initiative designed to promote biomedical entrepreneurship—don’t miss our upcoming webinar:

Wednesday, November 15, from 3:00-4:30 p.m. ET.

During the webinar, NIGMS and Center for Scientific Review staff will explain the goals and objectives of the initiative and answer your questions. You are encouraged to submit questions by November 13 to Krishan Arora.

To access the webinar, visit the WebEx Meeting page (link no longer available) and enter the meeting number 620 731 655 and the password “nigms.” If you are unable to attend online, you can join by phone by calling 1-650-479-3208 from anywhere in the United States or Canada and entering the access code 628 562 389.

NIGMS Staff Participating in the November 15 Webinar:

Krishan K. Arora, Program Director, NIGMS

Joseph Gindhart, Program Director, NIGMS

Christy Leake, Grants Management Team Leader, NIGMS

Allen Richon, Scientific Review Officer, NIH Center for Scientific Review

Slides will be available on the IDeA website following the event.

We look forward to talking with you soon.