Over the course of its 10-year existence, the Protein Structure Initiative has supported the development of new technologies and methods that improve the throughput of protein structure determination. Many of them apply to the production of purified proteins for functional and structural studies, and you don’t need access to major research centers to use them.
To help you take advantage of these resources, the PSI Structural Biology Knowledgebase offers a series of short articles summarizing tools and technologies developed by PSI-supported investigators. You may also request plasmid clones via the PSI Materials Repository .
As always, you can nominate targets for PSI investigators to solve.
If you’re going to the 2011 American Crystallographic Association meeting (May 28-June 2 in New Orleans) and want to know more about using these PSI products in your own lab, plan on attending my session, “PSI Tools for the Home Lab.” Also, the Structural Biology Knowledgebase will offer workshops at the International Conference of Structural Genomics (May 10-14 in Toronto).