To continue our efforts to catalyze the modernization of biomedical graduate education, we invite eligible NIGMS-funded T32 predoctoral training programs to submit administrative supplement requests (NOT-GM-19-015) to develop new curricular and training activities that enhance the program’s ability to: 1) provide graduate trainees with a strong foundation in research design and methods in areas related to conducting rigorous and transparent research to enhance reproducibility; 2) prepare students for diverse careers in the biomedical research workforce; 3) develop the knowledge and skills of trainees to enhance laboratory safety; and 4) develop the technical, operational, and professional skills of predoctoral biomedical researchers.
Since supplemental grant funding comes in a variety of flavors, with different purposes, it’s not surprising that there’s confusion about which kinds of supplements MIRA grantees may apply for and which they may not. Here’s a quick run-down.
NIGMS, along with other NIH Institutes and Centers, has partnered with the National Institute on Aging to grow the community of scientists actively engaged in research focused on Alzheimer’s Disease and Alzheimer’s Disease-Related Dementias (AD/ADRD). Details of this year’s AD/ADRD supplement program are provided in NIA’s Notice NOT-AG-18-008. If your research, research training, or research capacity-building grant is not currently focused on AD/ADRD and you have an inspiring new idea of potential value to the field that is within the scope of the funded Specific Aims of your current award, please consider this opportunity.
Research related to AD/ADRD might fall within the scope of an already-funded NIGMS award originally focused on, for example, an enzyme, transporter, or metabolic pathway being studied for its basic biological or physiological role (or a non-AD/ADRD-related medical condition) if you have recognized an exciting new implication for AD-type pathologies or their treatment. Funded projects developing analytical methods, tools or technologies, drug molecules, or drug delivery systems not previously intended for application to AD/ADRD might now appear to have potential in this area. Potential applicants are strongly encouraged to contact their program director to discuss their ideas for AD/ADRD research and how those relate to the Specific Aims currently funded. Decisions about scope are strictly the purview of NIH. Center and Resource grants that allow non-specified pilot projects should consider adding AD/ADRD projects if interest and expertise exist.
To continue our efforts to catalyze the modernization of biomedical graduate education, we invite eligible NIGMS-funded T32 predoctoral training programs to submit administrative supplement requests to develop new curricular and training activities to enhance the program’s ability to: 1) provide graduate trainees with a strong foundation in research design and methods in areas related to conducting rigorous and transparent research to enhance reproducibility (PA-18-756); 2) prepare students for diverse careers in the biomedical research workforce (PA-18-757); 3) develop the knowledge and skills of trainees to enhance laboratory safety (PA-18-758); and 4) develop the technical, operational, and professional skills of predoctoral biomedical researchers (PA-18-759).
Grantees should consider the following before applying:
UPDATE: For additional information, see the Notice of Availability of Administrative Supplements for Equipment Purchases for NIGMS Awardees, NOT-GM-18-022. Applications are due May 31.
NIGMS is offering administrative supplements of between $50,000 and $250,000 for the well-justified purchase of single pieces of equipment. In past years, we issued separate funding announcements (PA-15-089 and PA-16-125) for this purpose. This year, however, we will accept requests for equipment supplements from Principal Investigators (PIs) who hold NIGMS R01, R35, R37, or R15 awards under PA-18-591, Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional).
Eligible investigators are strongly encouraged to discuss potential requests with their program directors before submitting applications. Two or more NIGMS grantees at the same institution may submit separate but cross-referenced requests, where the funds requested reflect the actual proportion of the time that the shared equipment would be used by each PI. However, under no circumstances may a joint request exceed $400,000 in direct costs. The requested supplemental budget cannot exceed the total year direct cost amount of the parent award. PIs may not request future year funds. NIGMS strongly encourages investigators to seek matching funds from their institutions or elsewhere, and to ensure that follow-up expenses (such as maintenance contracts) will be covered from other available funds. Institutional contributions and commitment will be factored into funding decisions.
Our Maximizing Investigators’ Research Award (MIRA) program is still relatively new, so it’s not surprising that NIGMS staff frequently hear misconceptions about it. This post dispels five common MIRA myths.
Myth 1: Once an investigator is awarded a MIRA, the budget will never increase.
MIRA budgets may increase. At the time of the competing renewal application, a principal investigator (PI) may request an increase in funding. MIRAs with modest budgets that have been very productive and score very well could receive budget increases. Study sections will be asked to look at budget requests, and NIGMS staff will make determinations based on the reviewers’ recommendations and available funds.
Myth 2: Early stage investigators will receive more funding for their labs if they get an R01 than if they get a MIRA.
A MIRA PI who is an early stage investigator (ESI) has a higher probability of receiving more NIGMS funding than a non-MIRA ESI. Most ESI MIRA investigators receive $250,000 in direct costs per year. A recent analysis found that the vast majority of ESIs who have received an NIGMS R01 are initially awarded $200,000 or less, and most do not go on to receive a second NIGMS R01 during the first five years of their initial award. Thus, the total NIGMS funding for most relatively new investigators is higher with a MIRA.
Myth 3: MIRA discourages collaborative research.
NIGMS strongly endorses collaborative research, and this extends to the MIRA program. However, the MIRA concept is based on the idea that NIGMS will provide support to individual investigators’ research programs. Collaborators are expected to work together because of their mutual interest in a problem. The collaborator, in most cases, will support his or her efforts with independent funding, not through a subcontract from the MIRA. In cases where a collaborator’s efforts are well-justified, essential to the research program of the MIRA and cannot be supported by the collaborator, a consortium agreement can be included in the competing application.
NIGMS also encourages scientifically productive international collaborative research efforts. However, NIGMS will only provide funding for a foreign consortium arrangement when the collaboration is essential to the PI’s research program, represents a unique scientific opportunity and cannot be supported by the collaborator.
Myth 4: MIRA PIs cannot apply for administrative supplements.
MIRA PIs are eligible for Research Supplements to Promote Diversity in Health-Related Research and may be eligible for other types of administrative supplements, such as equipment supplements offered by NIGMS through notices in the NIH Guide for Grants and Contracts. In rare situations, NIGMS may provide a supplement for a piece of equipment that could not have been anticipated at the time the application was submitted.
Myth 5: MIRA PIs cannot apply for NIGMS training grants or conference grants.
MIRA PIs are eligible to apply for grants that support research resources, training, workforce development or diversity building, clinical trials, selected cooperative agreements, SBIR/STTRs, conference grants and the portion of a center grant or a P01 that is strictly a core. In addition, a MIRA PI may receive grants from other NIH institutes or centers, although when making funding decisions NIGMS always considers an investigator’s other support, as described on our Funding Policies page.
More information, including answers to frequently asked questions, is on the MIRA page.
On April 11, more than 150 people from across the country (plus many via videocast) participated in the NIGMS Symposium on Catalyzing the Modernization of Graduate Education. The goals of the meeting were to convene stakeholders to continue the momentum for positive change within the biomedical graduate education community and to showcase innovative experiments and approaches in Ph.D. training.
The morning session featured presentations highlighting the training expectations of graduate students, institutional approaches to reshaping graduate education programs and attributes employers look for when hiring early career scientists. These talks converged on the theme of ensuring that graduate education equips Ph.D. students with the scientific and professional skills they need to be successful in their careers.
After a presentation focusing on assessing the effectiveness of educational innovations, the speakers in the afternoon session described a variety of experiments in graduate education that are currently under way in various settings. The nine innovations featured in this session were augmented by an additional 32 posters presented during the lunch period.
UPDATE: To join this meeting, visit Webinar on Administrative Supplements to T32 Grants, PA-16-060 and click “OK.” The site is compatible with mobile devices. For a voice-only presentation, call 1-888-469-2151 from anywhere in the United States or Canada and enter the access code 8911526.
We’ll field your questions about the recently announced Availability of Administrative Supplements to NIGMS Predoctoral Training Grants during a webinar on Monday, Feb. 8, from 3:15-4:15 p.m. EST. Details about how to access the webinar online will be available soon. You can send questions to me ahead of time.
Since announcing this funding opportunity, we’ve received many inquiries. The following points address most of the common questions:
- The supplement is designed to provide support for the development and implementation of curricular activities aimed at providing graduate students with a strong foundation in research design and methods in areas related to conducting reproducible and rigorous research.
- To be eligible, your training grant must be active through at least June 30, 2018. Thus, training grants that might have received outstanding priority scores and are expected to be renewed effective July 1, 2016, are NOT eligible.
We recently analyzed outcomes of the NIGMS Research Supplements to Promote Diversity in Health-Related Research (referred to here as the Diversity Supplement Program or DSP), which provides investigators holding active NIGMS research grants with supplemental funds to support scholars from groups underrepresented in biomedical science. Using a public search approach, we could track a large proportion of participants—but not all—through doctoral training and into various careers. We assessed the educational and career outcomes for undergraduate, graduate student and postdoctoral participants supported by supplements between 1989 and 2006, and we encourage you to explore the report.