CBB Division Director Catherine Lewis Retires

Dr. Catherine D. Lewis

Catherine D. Lewis, director of the NIGMS Division of Cell Biology and Biophysics (CBB), retired in January after more than 30 years of service at the NIH. Throughout her career, Cathy was widely recognized for her scientific foresight and leadership, including the early recognition of important emerging research opportunities in molecular biology, biophysics and microscopy. Her tireless work behind the scenes ensured that these transformational new research approaches were seamlessly integrated into the NIH portfolio and able to grow rapidly.

Cathy earned an M.S. and Ph.D. in biochemistry from Princeton University and joined NIH in 1983 as a staff fellow at NIDDK in the lab of Gary Felsenfeld, where she studied chromatin structure and the regulation of beta-globin gene expression during development.

Her career at NIGMS started in 1989, when Cathy moved to the Institute as a program director in the Genetics Division—led at the time by Judith Greenberg. She managed grants on cell nuclear structure and function and was instrumental in the development of programs focused on epigenetic regulation. Eight years later, Cathy became CBB’s Biophysics Branch chief. In that role, she at one point managed nearly 400 grants, some of which led to breakthroughs such as the structure of the ribosome. She also initiated NIGMS programs focused on new single-molecule methods and nanotechnology. In 2006, Cathy took over as director of CBB. During this period, she oversaw changes in the direction of the NIGMS Protein Structure Initiative, promoted advances in high-resolution optical microscopy and cellular imaging, and led efforts to support atomic resolution cryo-electron microscopy, including a new Common Fund initiative.

During her tenure at NIH, Cathy received two NIH Director’s Awards, for her work on trans-NIH initiatives and her leadership on science education in elementary schools.

Cathy’s door was always open to all, and her advice was constantly sought by colleagues, not only in her own division, but widely across NIGMS and NIH.

Most importantly, Cathy maintained warm professional and personal relationships with those around her, while getting things done and influencing others. “Leading a division that worked well and where people respected each other and got along is something that I’m happy to have been involved in,” she says.

Working in the CBB division was fun, because she helped make it so. She will be missed.

Stephanie Constant to Direct NIGMS Office of Scientific Review

Photo of Dr. Stephanie L. ConstantI’m pleased to announce that Stephanie Constant will be joining us in early 2017 as the new chief of our Office of Scientific Review.

Stephanie is currently a scientific review officer at NIH’s National Heart, Lung, and Blood Institute, where her review portfolio is primarily focused on training and career development programs to promote diversity in the biomedical workforce. She also worked on detail in NIH’s Office of Extramural Research, where she contributed to developing and updating policy guidelines to enhance the NIH peer review process. Prior to joining NIH, she was a tenured associate professor in the Department of Microbiology, Immunology and Tropical Medicine at George Washington University. Her research included studies on the regulation of leukocyte migration in acute and chronic inflammation and on the mechanisms of immunomodulation by parasite products.

Stephanie’s deep knowledge of NIH review policies and practices and expertise in the review of training and diversity grant applications make her an ideal fit for this key position in our Institute. Please join me in welcoming her to NIGMS.

For more about Stephanie, see our news announcement.

Special Issue of CBE-Life Sciences Education Advances the Science of Broadening Participation

NIGMS’ longstanding support of and commitment to programs that promote workforce diversity have contributed to significant progress Exit icon, but persistent representation gaps along demographic lines remain in the ranks of both independent investigators and scientific leadership. These gaps lead to the loss of valuable contributors from the talent pool and limit the ability of the biomedical community to identify and address critical scientific and societal concerns. A special issue of CBE-Life Sciences Education Exit icon, published September 1, provides the broader community with a chance to assess the progress made and plan for a future in which we cultivate and harness all available talent.

Attendees at the INBRE-sponsored Mississippi Academy of Sciences annual meeting are featured on the cover of this special issue.

The papers in this issue, which I edited with Pat Marsteller of Emory University, fit four main themes:

  • Innovative and effective interventions or approaches for broadening participation.
  • Mechanistic explanations for why certain approaches have been effective.
  • Novel insights about institutional and systemic factors that influence broadening participation efforts.
  • Syntheses of research and practices that provide a “plan of action” heading forward.

NIGMS leadership, staff and grantees authored 11 of the 35 features, editorials, essays and articles in the special issue. While all of the papers focus on topics of importance to developing a diverse scientific workforce, I wanted to call your attention to a few representative articles:

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Rochelle Long to Lead Pharmacology, Physiology, and Biological Chemistry Division

Dr. Rochelle LongI’m very pleased to announce the selection of Rochelle Long as director of our Division of Pharmacology, Physiology, and Biological Chemistry (PPBC). Rochelle is a pharmacologist who has played leading roles in fostering research in pharmacogenomics through national and international collaborations.

She established and oversees the trans-NIH Pharmacogenomics Research Network and has catalyzed associated partnerships, such as the Global Alliance for Pharmacogenomics and the Clinical Pharmacogenetics Implementation Consortium.

Rochelle has worked in PPBC since 1990, starting as a program director and rising to become chief of its Pharmacological and Physiological Sciences Branch in 1998. She has served as acting division director since Mike Rogers’ retirement in May 2015.

Rochelle’s plans include building bridges across scientific disciplines, working to strengthen emerging fields and promoting cross-disciplinary research. These are goals across the Institute—they are reflected in our strategic plan—and they’re particularly relevant for a broad-ranging division like PPBC.

Since I’ve had the opportunity to interact with her for several years, I know how skilled Rochelle is at organizing, motivating and generating cohesion among groups of people. These qualities will serve her well as PPBC director and as a member of the NIGMS senior leadership team.

For more about Rochelle, see our news announcement.

Sharing Our Passion for Science

NIGMS Director Dr. Jon R. Lorsch explains a protein letter computer activity to a young participant at the USA Science and Engineering FestivalA few weeks ago, 23 NIGMS volunteers and I spent an amazing day with thousands of highly engaged kids, their parents and other science enthusiasts of all ages at the Washington, DC, Convention Center. We were participating in the USA Science & Engineering Festival, the largest STEM event in the nation.

The NIGMS booth was a big hit! Our theme was Cell-e-bration of Science,
with activities that included spelling names with protein letters and a
“selfie station” with science-related props.Festival participants at the NIGMS selfie station holding science themed props in front of a colorful backdrop of a cell

Getting young people interested in science is essential to building a vibrant and innovative research enterprise. The Science & Engineering Festival, with more than 365,000 participants, gave us a chance to share our passion for science with thousands of young people. Hopefully, some of the kids we met are now thinking about careers as scientists.

NIGMS staff volunteer demonstrating how the protein letter computer activity worksI encourage you to share your own enthusiasm for science with young people whenever you have the opportunity. Whether you judge a science fair, speak at a career day or have students visit your lab, you put a human face on science and help students see it as an exciting, fulfilling and worthy career choice.

 

Long-Time Scientific Review Chief Helen Sunshine Retires

Dr. Helen SunshineHelen Sunshine, who led the NIGMS Office of Scientific Review (OSR) for the last 27 years, retired in April. Throughout her career, she worked tirelessly to uphold the highest standards of peer review.

Helen earned a Ph.D. in chemistry at Columbia University and joined the NIH intramural program in 1976, working first as a postdoctoral fellow and then as a senior research scientist in the Laboratory of Chemical Physics, headed by William Eaton.

In 1981, Helen became a scientific review officer (SRO) in OSR and was appointed by then-NIGMS Director Ruth L. Kirschstein to be its chief in 1989. During her career in OSR, she oversaw the review of many hundreds of applications each year representing every scientific area within the NIGMS mission.

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